Deterministic Storage of Liquid Plugs in Microfluidic Channels Using Passive Valves
نویسندگان
چکیده
This work describes a microfluidic device that is capable of sorting liquid plugs and storing them into pockets without actuators (active valves). We programmed the deterministic fluid flow using burst-valves with different geometries.
منابع مشابه
Using three-phase flow of immiscible liquids to prevent coalescence of droplets in microfluidic channels: criteria to identify the third liquid and validation with protein crystallization.
This manuscript describes the effect of interfacial tensions on three-phase liquid-liquid-liquid flow in microfluidic channels and the use of this flow to prevent microfluidic plugs from coalescing. One problem in using microfluidic plugs as microreactors is the coalescence of adjacent plugs caused by the relative motion of plugs during flow. Here, coalescence of reagent plugs was eliminated by...
متن کاملHigh-pressure on-chip mechanical valves for thermoplastic microfluidic devices.
A facile method enabling the integration of elastomeric valves into rigid thermoplastic microfluidic chips is described. The valves employ discrete plugs of elastomeric polydimethylsiloxane (PDMS) integrated into the thermoplastic substrate and actuated using a threaded stainless steel needle. The fabrication process takes advantage of poly(ethylene glycol) (PEG) as a sacrificial molding materi...
متن کاملValves for autonomous capillary systems
Autonomous capillary systems (CSs) are microfluidic systems inside which liquids move owing to capillary forces. CSs can in principle bring the high-performances of microfluidic-based analytical devices to near patient and environmental testing applications. In this paper, we show how wettable capillary valves can enhance CSs with novel functionalities, such as delaying and stopping liquids in ...
متن کاملTorque-actuated valves for microfluidics.
This paper describes torque-actuated valves for controlling the flow of fluids in microfluidic channels. The valves consist of small machine screws (> or =500 microm) embedded in a layer of polyurethane cast above microfluidic channels fabricated in poly(dimethylsiloxane) (PDMS). The polyurethane is cured photochemically with the screws in place; on curing, it bonds to the surrounding layer of ...
متن کاملMicrofluidic Devices for Biotechnology and Organic Chemical Applications
Imagine if you could combine the power and capabilities of an entire laboratory in the palm of your hand. Advances in microfluidic chip technology promise to integrate and miniaturize multiple lab processes into a single palm-sized device. The advantages of these lab-on-a-chip devices, sometimes also referred to as micro total analysis systems (μTAS), compared with conventional bench-scale syst...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2008